1) NO. 3 LOUISVILLE AT NO. 5 CLEMSON
How impressive has Louisville (4-0, 2-0 ACC) been? Consider this: The Cardinals are favored against a top-5 team on the road. Their offensive statistics look like a series of crazy typos – 682 yards per game, 64 points per game. And Lamar Jackson continues to be a superhero and a clear favorite for the Heisman. But a little perspective never hurts: Clemson (4-0, 1-0) is a difficult place to win, the Tigers’ defense allows only 11 points per game and Clemson QB Deshaun Watson is going to be a top-10 draft pick . It’s still relatively early in the season, but the winner of this one likely will win the ACC’s Atlantic division (unless Florida State can pull itself together soon). 8 p.m. WVEC
2) NO. 8 WISCONSIN AT NO. 4 MICHIGAN
So many college games feature teams with wide-open offenses and questionable defenses. Here, not so much. Michigan (4-0, 1-0 Big Ten) is a surprisingly large favorite (10 points), but Wisconsin can at least keep it close by doing two things: stop the Wolverines’ rushing attack and put points on the board. Michigan averages 230 rushing yards per game and racked up 326 last week against Penn State. Wisconsin (4-0, 1-0) has allowed only 80 rushing yards per game, so something’s going to give there. 3:30 p.m., WVEC
3) NORTH CAROLINA AT NO. 12 FLORIDA STATE
This game has “shootout” written all over it. The offense for UNC (3-1, 1-0 ACC) has been impressive, with QB Mitch Trubisky throwing for more than 1,300 yards and 10 TDs with no interceptions. A loss would end Florida State’s dreams of a national title, and maybe even its chances at an ACC title. The Seminoles’ best bet is their best player, RB Dalvin Cook. UNC’s run defense has been lousy, allowing more than 240 yards per game. Florida State (3-1, 0-1) has to get a few stops on defense, though, and those have been surprisingly hard to come by. The Seminoles are last among Power 5 conference teams in yards allowed per play (6.78) and have have allowed 30 or more points in all three games against Football Bowl Subdivision opponents. 3:30 p.m., ESPN
4) NO. 14 MIAMI AT GEORGIA TECH
Who would’ve guessed there would be so many interesting ACC games? Finally, we’re going to learn something about Miami, unless you think that win over Florida Atlantic was meaningful. The ACC’s Coastal division is shaping up to be a free-for-all, and Georgia Tech needs a win to stay in touch with the rest of the teams near the top. Noon, ESPN2
5) NO. 11 TENNESSEE AT NO. 25 GEORGIA
Tennessee (4-0, 1-0 SEC), the team that barely beat Appalachian State and Ohio, can put itself in a strong position with a win. The Volunteers can use all the momentum they can get, because after this game, the schedule gets much harder. Georgia (3-1, 1-1) is in dire straits regardless because star RB Nick Chubb is hurt and QB Jacob Eason is a freshman. 3:30 p.m., WTKR
ALSO ON THE AIR
Notre Dame vs. Syracuse, noon, ESPN
No. 22 Texas at Oklahoma State, noon, WVEC
Rutgers at No. 2 Ohio State, noon, BTN
UCF at East Carolina, noon, CBSSN
SMU at Temple, noon, ESPNEWS
Northwestern at Iowa, noon, ESPNU
No. 13 Baylor at Iowa State, noon, FS1
No. 23 Florida at Vanderbilt, noon, SEC
Virginia at Duke, 12:30 p.m., WGNT, 850AM
Mercer at VMI, 1:30 p.m., 1650AM
Howard at Norfolk State, 2 p.m., 1310AM, 91.1FM
Illinois at No. 15 Nebraska, 3:30 p.m., ESPN2
Minnesota at Penn State, 3:30 p.m., BTN
Navy at Air Force, 3:30 p.m., CBSSN, 102.1FM
Kansas State at West Va., 3:30 p.m., ESPNU
Tulane at UMass, 3:30 p.m., WTVZ
No. 9 Texas A&M at S. Carolina, 4 p.m., SEC
Oklahoma at No. 21 TCU, 5 p.m., WVBT
Old Dominion at Charlotte, 5 p.m., 94.1 FM
W. Michigan at C. Michigan, 7 p.m., CBSSN
Kentucky at No. 1 Alabama, 7 p.m., ESPN
Memphis at No. 16 Mississippi, 7 p.m., ESPN2
South Florida at Cincinnati, 7 p.m., ESPNU
Missouri at LSU, 7:30 p.m., SEC
No. 17 Michigan State at Indiana, 8 p.m., BTN
No. 19 S. Diego St. at S. Ala., 8 p.m., ESPNEWS
Arizona State at USC, 8:30 p.m., WVBT
Utah St. at No. 24 Boise St., 10:15 p.m., ESPN2
Wyoming at Colorado State, 10:15 p.m., ESPNU
Fresno State at UNLV, 10:30 p.m., CBSSN
ALSO IN THE TOP 25
No. 18 Utah at California, 6 p.m.
No. 20 Arkansas vs. Alcorn State, Noon
?Brian Root, 757-446-2368, brian.root@pilotonline.com
