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From garden to RX – plants that have been responsible for medicines

Many common garden plants, like Madagascar periwinkle (a.k.a. vinca), do more than just add color to our gardens. They can also be the source of powerful life-changing pharmaceuticals.
The Virginian-Pilot
Many common garden plants, like Madagascar periwinkle (a.k.a. vinca), do more than just add color to our gardens. They can also be the source of powerful life-changing pharmaceuticals.
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Many common garden plants, like Madagascar periwinkle (a.k.a. vinca), do more than just add color to our gardens. They can also be the source of powerful life-changing pharmaceuticals.
Many common garden plants, like Madagascar periwinkle (a.k.a. vinca), do more than just add color to our gardens. They can also be the source of powerful life-changing pharmaceuticals.

When thinking of plants and medicine, usually herbal remedies are what come to mind. Botanical remedies have been used throughout human history by civilizations around the world. Today these natural cures are still widely practiced and have become a modern industry. Of the many plants used for medical research and treatments, certain plants have become staples in the pharmaceutical industry. These plants are valued for their naturally occurring chemical compounds used in the production of modern pharmaceutical drugs.

The Pacific yew (Taxus brevifolia) is a coniferous tree native to the Pacific coast of North America. This tree became an important part of cancer treatment when it was discovered that paclitaxel, a compound in the bark, could stop cell growth and division. This compound is the main ingredient of Taxol, a staple chemotherapeutic drug. The drug is now used in the treatment of cancers of the head, neck, breast, lung, pancreas and esophagus.

The trees in the genus Cinchona are the source of an important ingredient used to treat malaria. Native to South America, this tree’s bark contains many alkaloids, one of which is quinine. Classified as an antimalarial, quinine is used to target the infectious organisms responsible for malaria. Quinine is also used to treat babesiosis infections spread by ticks.

Madagascar periwinkle (Catharanthus roseus), a common garden annual, is another plant used in the treatment of cancers. The leaves of this plant contain two alkaloids, vinblastine and vincristine, which are used in chemotherapy drugs. Both chemicals operate by slowing or stopping cell growth and are used to treat Hodgkin’s disease and non-Hodgkin’s lymphoma. Vinblastine is specifically used to treat testicular cancer, breast cancer and gestational tumors as a secondary option. Vincristine is used to treat kidney cancer, nerve cell cancers and muscle cancers in children.

Chili pepper plants (Capsicum annum) are grown in warm climates around the world. Native to Central and South America, the fruits of this plant are commonly used for food, spices and in ornamental gardens. Along with these uses, capsicum, a natural chemical found in the fruit, is used to produce painkillers. Capsicum is primarily used in ointments and creams that treat rheumatoid arthritis, osteoarthritis and various other painful medical conditions.

There are hundreds of species of yams (Dioscorea) found in the world. While commonly grown as food, some species are grown for the compound diosgenin. Diosgenin is used in the laboratory production of estrogens and DHEA. Estrogens and DHEA are used to treat various medical conditions that occur in women during menopause. Estrogens are also used to relieve the symptoms of certain breast and prostate cancers.

From common sicknesses to deadly diseases, plants have always been a key part of medicinal practices. As herbal medicines become more popular and the industry grows, it is important to know the differences between herbal remedies and pharmaceuticals. While herbal remedies can be taken directly or easily prepared at home, pharmaceutical plants are harvested for chemicals used in the laboratory production of prescription medications. Though pharmaceutical plants are not as well-known as herbals, both play key roles in promoting health and easing suffering. This is precisely why it is so important for our species to leave plenty of room in this world for other species. After all, we never know where the next miracle drug might come from.